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Cisplatin cardiomyopathy

WebJan 10, 2011 · Combinations of cisplatin with other anticancer drugs as methotrexate, 5-fluorouracil, bleomycin and doxorubicin are associated with lethal cardiomyopathy ( … WebOct 11, 2024 · Weakening of the heart muscle (cardiomyopathy) Heart rhythm problems (arrhythmia) Heart attack Stroke High blood pressure Blood clots Whether you're at risk …

Cardiotoxicity of cisplatin-based chemotherapy in advanced non …

WebSummary: Congestive cardiomyopathy is found among people who take Cisplatin, especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months. The phase IV clinical study analyzes which people take Cisplatin and have Congestive cardiomyopathy. It is created by eHealthMe based on reports of 79,691 people who … WebAlthough cisplatin (cisPt) is one of the most often used cytotoxic drugs in the treatment of cancer, its clinical application is associated with nephrotoxicity 掌桥科研 一站式科研服务平台 bitly logo https://newdirectionsce.com

Wogonin Alleviates Cisplatin-induced Cardiotoxicity in Mice ...

WebApr 11, 2024 · Cisplatin is a widely used chemotherapeutic agent for treatment of various cancers. However, treatment with cisplatin is associated with drug resistance and several adverse side effects such as nephrotoxicity, reduced immunity towards infections and … WebThis study has been initiated to investigate whether endogenous carnitine depletion and/or carnitine deficiency is a risk factor during development of cisplatin (CDDP)-induced cardiomyopathy and if so, whether carnitine supplementation by propionyl-L-carnitine (PLC) could offer protection against this toxicity. WebMar 12, 2015 · We previously demonstrated that the increase in troponin I (TnI) soon after high-dose chemotherapy (HDC) is a strong predictor of left ventricular dysfunction and poor cardiac outcome, particularly in patients showing a persistent TnI increase. 5,6 This finding has important clinical implications and allows the identification of patients at high risk of … data did not shown

Cisplatin and Congestive cardiomyopathy, a phase IV clinical …

Category:Effects of acute in vivo cisplatin and selenium treatment on ...

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Cisplatin cardiomyopathy

Chemotherapy Agents That Cause Cardiotoxicity - U.S.

WebJan 1, 2013 · Patients receiving cisplatin-based chemotherapy may experience coronary artery diseases, arrhythmias, and cardiomyopathy 3). Moore et al. have reported cases of arterial thrombosis with subsequent ... WebAug 1, 2012 · Traditional and novel chemotherapy agents can damage the heart or peripheral blood vessels, or cause problems with clotting or blood lipids. Some …

Cisplatin cardiomyopathy

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WebNov 17, 2024 · joint or muscle pain. loss of appetite. lower back or side pain. muscle tremors. nausea or vomiting. rapid, deep breathing. red, irritated eyes. red skin lesions, often with a purple center. restlessness. WebApr 2, 2024 · Cardiomyopathy (kahr-dee-o-my-OP-uh-thee) is a disease of the heart muscle that makes it harder for the heart to pump blood to the rest of the body. Cardiomyopathy can lead to heart failure. The main types …

WebApr 11, 2024 · The package insert for Adriamycin states that lifetime cumulative doses above 550 mg/m2 (21-day cycles) are associated with an increased risk of cardiomyopathy. In people at higher risk of cardiotoxicity, the maximum cumulative dose of doxorubicin should be limited to less than 400. WebDec 6, 2024 · weakness in the arms, hands, legs, or feet Less common Blood in the urine or stools difficult or labored breathing pinpoint red spots on the skin shortness of breath (severe) slow heartbeat tightness in the chest wheezing Incidence not known Anxiety blue lips, fingernails, or skin difficult or troubled breathing fainting fast heartbeat

WebNational Center for Biotechnology Information WebWARNING: CARDIOMYOPATHY, INFUSION REACTIONS, EMBRYO-FETAL TOXICITY, and PULMONARY TOXICITY See full prescribing information for complete boxed warning Cardiomyopathy: trastuzumab products can result in subclinical and clinical cardiac ... Cisplatin was administered at 80 mg/m on Day 1 and the

WebMay 4, 2024 · Signs and symptoms of dilated cardiomyopathy may include: Fatigue. Shortness of breath (dyspnea) during activity or while lying down. Reduced ability to exercise. Swelling (edema) in the legs, ankles, …

WebThis table is provided as an example of how to administer this regimen; there may be other acceptable methods. This regimen must be administered by a clinician trained in the use of chemotherapy, who should use independent medical judgment in the context of individual circumstances to make adjustments, as necessary. bit ly/mcgpuserWebJun 1, 2013 · Cisplatin-based combinations are standard regimens in the treatment of advanced non-small cell lung cancer, significantly improving survival of patients. … data directory is not empty initdbWebApr 21, 2024 · If you’re receiving carboplatin or cisplatin chemotherapy, talk to your doctor about the risks to your hearing. Heart problems Chemotherapy can lead to high blood … bitly meaningWebJun 1, 2013 · Cardiotoxicity is a well known consequence of cancer chemotherapy. Cisplatin-based combinations are standard regimens in the therapy of advanced non-small cell lung cancer. Administration of cisplatin-containing chemotherapy causes significant oxidative and nitrosative stress in some patients. bitly links send to skypeWebJul 27, 2024 · Conventional doxorubicin: Treatment (in combination regimens with cisplatin, methotrexate, and vinblastine) of invasive and advanced bladder carcinoma. ... Pediatric patients are at increased risk for developing delayed cardiotoxicity; doxorubicin-induced cardiomyopathy impairs myocardial growth as pediatric patients mature, … bitly mcm propelWebMar 17, 2024 · Cardiotoxicity is defined as any heart injury (functional or structural) related to cancer treatment, taking into consideration chemotherapy, radiotherapy … bit ly mfusaachbitly link scanner