Cd300a macrophage
WebCD300a, a membrane protein expressed on myeloid lineages and specific subsets of CD4(+) T cells, has been reported to have inhibitory activities in cellular activation. … WebDAP12 and FcϵRIγ contain an immunoreceptor tyrosine-based activation motif in their cytoplasmic regions, whereas DAP10 contains a YXXM motif, a potential Src homology 2 domain-binding site for the p85 regulatory …
Cd300a macrophage
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WebMar 14, 2013 · The CD300 family of molecules modulates a broad and diverse array of immune cell processes via their paired activating and inhibitory receptor functions. … Webmyeloid cells [30]. The CD300a and CD300c orthologues CLM-8 and CLM-4 were identified on IL-12-activated NK cells and B lymphocytes but not on T lymphocytes. The CLM molecules studied to date are expressed on mouse splenocytes, granulocytes and macrophages, DC and mast cells derived in vitro from bone marrow (BM). Again, the
WebMar 29, 2024 · CD300a is an inhibitory receptor expressed by human natural killer (NK) cells, but surprisingly, not all NK clones are inhibited in a CD300a-dependent manner. … WebJun 2, 2011 · CD300a belongs to the CD300 family of activating/inhibitory receptors whose genes are clustered in human chromosome 17. 12 CD300a is a type I transmembrane receptor with an IgV-like extracellular domain and a cytoplasmic tail that has 3 classic ITIM motifs 12,13 and is expressed on cells of both lymphoid and myeloid lineages. 12 Its …
WebJan 18, 2024 · Born in 1965, Katherine Gray attended the Rhode Island School of Design and the Ontario College of Art, in Toronto, Canada. A huge proponent of handiwork and … WebJan 1, 2014 · In mice, disruption of the Cd300a gene resulted in pro-inflammatory activation of peritoneal macrophages, identifying CD300a-mediated inhibitory signaling in macrophages as a critical regulator of ...
WebAug 15, 2008 · They are expressed on monocytes, macrophages, granulocytes, DCs, T lymphocytes, and NK cells, and they have regulatory functions in leukocytes. 24,27 Recently, we showed that expression of the CD300a/c molecules identifies a functionally distinctive CD4 + T-lymphocyte subpopulation. 28 This study addresses the expression …
WebMar 29, 2024 · CD300a induction by the hypoxic environment represents a mechanism of regulation of monocyte/macrophage pro-inflammatory responses at pathologic sites Title: Identification of CD300a as a new hypoxia-inducible gene and a regulator of CCL20 and VEGF production by human monocytes and macrophages. religious beliefs of ancient egyptiansWebJun 24, 2014 · These results identify CD300a-mediated inhibitory signaling in macrophages as a critical regulator of intestinal immune homeostasis. Scientific Reports - PPARβ/δ activation of CD300a controls ... religious beliefs in the middle coloniesWeb蛋白酪氨酸磷酸酶C型受體 （英語： Protein tyrosine phosphatase, receptor type, C ， 縮寫 ： PTPRC ）是一個由PTPRC 人類 基因 編碼的 酶 [6] 蛋白酪氨酸磷酸酶C型受體又叫做45號 分化簇 抗原 ，以前曾叫 白細胞常見抗原 （英語： leukocyte common antigen ， 縮寫 … religious beliefs of baha\u0027iWebNational Center for Biotechnology Information prof. dr. florian schützWebMay 12, 2024 · LPC is released from apoptotic cells and binds to the G-protein-coupled receptor G2A on macrophages, ... Choi SC, Coligan JE, Borrego F . Human CD300a binds to phosphatidylethanolamine and ... prof dr florian pfabWebMar 16, 2024 · Background: CD300a is an inhibitory receptor (IR) expressed on several leukocytes, including mast cells (MCs) and macrophages (MΦ), important cells in … prof. dr. florian matthesWebOct 4, 2024 · CD300a seems to regulate the activity of various immune cells types involved in the process, including neutrophils, macrophages, and lymphocytes. Title: The immunoreceptor CD300a controls the intensity of inflammation and dysfunction in a model of Ag-induced arthritis in mice. prof dr fegg münchen